09 Apr Ketamine Therapy in Naples, FL: A New Path for Treatment-Resistant Depression

Depression can be a heavy burden—especially when traditional medications and therapy haven’t worked. At MY Self Wellness, based in beautiful Naples, Florida, we understand just how isolating and frustrating treatment-resistant depression (TRD) can be.

According to a study by the CDC, people diagnosed with major depressive disorder are up to 30 times more likely to suffer from TRD. If this sounds familiar, and you’ve been searching for relief that actually works, ketamine therapy may offer the rapid, lasting breakthrough you deserve.

Recognizing the Signs of Treatment-Resistant Depression

Depression isn’t always obvious, and when symptoms persist—despite every effort—you might be dealing with TRD. Here are some common signs:

• No long-term relief from antidepressant medications

• No noticeable changes after consistent therapy or counseling

• Ongoing sleep disturbances (3+ nights a week)

• Sudden changes in appetite—overeating or undereating

• Recurring thoughts of suicide or self-harm

Sometimes people feel brief improvements when switching meds or upping doses—but short-term change doesn’t always equal long-term healing. That’s where ketamine comes in.

How Ketamine Therapy Works at MY Self Wellness

At our Naples ketamine clinic, every treatment begins with a comprehensive medical and emotional evaluation. We assess your past experiences with medications, any coexisting conditions, and your overall health to ensure you’re a good fit for therapy.

Our preferred method is intramuscular (IM) injection, not IV. Why? Because we’ve found that IM ketamine offers a deeper, more transformational experience that’s better aligned with our psychedelic-informed healing approach. Each session is monitored by a licensed, compassionate medical team in a calming, spa-like environment where your comfort is our priority.

What Makes Ketamine Therapy So Unique?

✧ Few Side Effects

Ketamine is generally well-tolerated, with minimal side effects. Some people feel relaxed and dissociative—floaty or detached—during the session. These sensations are part of the healing experience and subside soon after treatment.

✧ Fast-Acting Relief

Unlike antidepressants that can take weeks to show any sign of relief, ketamine often works within hours. Many of our Naples patients report feeling lighter, clearer, and more emotionally balanced by the time they leave their first session.

✧ Works When Other Treatments Haven’t

Ketamine targets the glutamate system, creating new neural connections and helping the brain rewire itself—offering new emotional patterns and faster healing.

Frequently Asked Questions About Ketamine Therapy

Am I a good candidate for ketamine therapy?
If you’ve been diagnosed with depression that hasn’t responded to traditional methods—and you’re in stable physical health—you may be an excellent candidate.

Can I continue my antidepressants?
In most cases, yes. Many patients benefit from combining ketamine with their current medication. We’ll help you decide what’s safest and most effective.

How long do the effects last?
Every person is different. For many, the benefits of ketamine last days to several weeks. We typically start with a series of sessions spaced out to build a strong foundation.

Can I receive multiple treatments?
Absolutely. Many of our patients find that a personalized maintenance plan—including ketamine therapy and integration support—helps them sustain long-term wellness.

Healing Happens Here in Naples

At MY Self Wellness, we don’t just treat symptoms—we support total transformation. From your first phone call to post-treatment integration, you’ll be cared for by a team that has been where you are and come out on the other side.

We’re proud to serve Naples, Fort Myers, Bonita Springs, Cape Coral, and Marco Island, offering ketamine therapy in a safe, uplifting, and judgment-free space.

✨ Your New Life Begins Here

If you or someone you love is struggling with depression that just won’t lift, you’re not alone—and you’re not out of options. Ketamine therapy could be the turning point you’ve been hoping for.

Contact us today to schedule your free consultation and let us guide you toward a new beginning.